CURRICULUM VITAE

Rainer Schindl

Personal

Born 1 October 1977, Steyr, Austria

Education

1984 - 1988	Elementary School in Steyr, Münichholz
1988 - 1996	Grammar School (Bundesrealgymnasium) in Steyr
1996 - 1997	Civilian Service
1997 - 2002	University of Linz M.S. Technical Physics
2002 - 2005	University of Linz Ph.D. Technical Sciences

Awards

Erwin-Wenzl-Preis 2002

Academic Record

2001 - 2002	Graduate fellow at the Institute for Biophysics, University of Linz Diploma thesis: Molecular analysis of calcium influx in mast cells
2002 - 2005	Postgraduate fellow at the Institute for Biophysics, University of Linz PhD thesis: Molecular architecture and function of TRP channels
2006 - present	Postdoctoral fellow at the Institute for Biophysics, University of Linz

Memberships

Biophysical Society USA, Stadtkapelle Steyr

Publications:

Schindl, R., Kahr, H., Graz, I., Groschner, K., and Romanin, C. (2002)
Store-depletion activated CaT1 currents in RBL mast cells are inhibited by 2-APB: Evidence for a regulatory component that controls activation of both CaT1 and CRAC channels.
J. Biol. Chem. 277, 30, 26950-26958.
Poteser M., Wakabayashi I., Rosker C., Teubl M., Schindl R., Soldatov N.M., Romanin C., and Groschner K. (2003)
Crosstalk between voltage-independent Ca2+ channels and L-type Ca2+ channels in A7r5 vascular smooth muscle cells at elevated intracellular pH - Evidence for functional coupling between L-type Ca2+ channels and a 2-APB- sensitive cation channel
CIRC RES 92 (8): 888-896
Kahr H., Schindl R., Fritsch R., Heinze B., Hofbauer M., Hack M.E., Mortelmaier M.A., Groschner K., Peng J.-B., Takanaga H., Hediger M.A. and Romanin C (2004)
CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells.
J Physiol. 557(Pt 1):121-32.
Derler I, Hofbauer M, Kahr H, Fritsch R, Muik M, Kepplinger K, Hack ME, Moritz S, Schindl R, Groschner K, Romanin C.
Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation.
J Physiol. 2006 Nov 15;577 (Pt 1):31-44.
Schindl R, Romanin C.
Assembly domains in TRP channels.
Biochem Soc Trans. 2007 Feb;35 (Pt 1):84-5.
Schindl R, Frischauf I, Kahr H, Fritsch R, Krenn M, Derndl A, Vales E, Muik M, Derler I, Groschner K, Romanin C.
The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.
Cell Calcium. 2008 Mar;43 (3):260-9. Schindl R, Weghuber J, Romanin C, Schweyen RJ. Mrs2p forms a high conductance Mg2+ selective channel in mitochondria.
Biophys J. 2007 Dec 1;93 (11):3872-83.
Muik M, Frischauf I, Derler I, Fahrner M, Bergsmann J, Eder P, Schindl R, Hesch C, Polzinger B, Fritsch R, Kahr H, Madl J, Gruber H, Groschner K, Romanin C.
Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.
J Biol Chem. 2008 (in press)

Oral Presentations

Schindl R., Kahr H., Fritsch R., Heinze B., Hofbauer M., Hack M.E., Groschner K., Peng J.B., Takanaga H., Hediger M.A., and Romanin C. (2004) CaT1 is not a component of CRAC in mucosal-type mast cells. Deutsche Pharmakologische Gesellschaft, Mainz, Germany
Rainer Schindl, Irene Frischauf, Heike Kahr, Reinhard Fritsch, Alexandra Derndl, Klaus Groschner and Christoph Romanin (2005) Homo- and heteromultimerisation of TRPC4 and TRPC5 is dependent on ankyrin-like repeats Deutsche Physiologische Gesellschaft, München, Germany
Rainer Schindl, Heike Kahr, Annarita Graziani, Ursula Utzmann, Alexander Wagner, Marlene Hack, Reinhard Fritsch, Klaus Groschner and Christoph Romanin (2007) TRPC1 modulates TRPV6 channel activity. TRP Meeting, Bath, England
Schindl Rainer, Weghuber Julian, Froschauer Elisabeth M, Svidova Sona, Schweyen Rudolf J, Romanin Christoph (2008) Functional comparison of the Mg2+ permeable channels Lpe10 and Mrs2 in mitochondria. Biophysical Society Meeting, Long Beach, California, USA

Invited Presentations

Institute for Pharmaceutical Sciences, Pharmacology und Toxicology, K. Franzens-University of Graz (2002, 2007)
Institute of Physical Biology, University of South Bohemia, Nove Hrady, Czech Republic (2005)
Max. F. Perutz Laboratories, Department of Genetics, University of Vienna (2005, 2006)
Annual Linz Winter Workshop/School (2007)

Teaching Activities

Practical Course in Biophysics
Practical Course in Patch Clamp

JKU | Biophysics | Ion Channel Group